In recent years, additive manufacturing of NGCs has effectively solved the above problems due to its simple and efficient manufacturing method, and it can be used as the carrier of bioactive substances. Nerve guidance conduit (NGC) serves as the most promising alternative to autologous transplantation, but its production process is complicated and it is difficult to effectively combine growth factors and bioactive substances. Nerve autografting is first-line treatment of peripheral nerve injuries (PNIs) but can result in loss of function of the donor site, neuroma formation, and prolonged operative time. 3Department of Burn Surgery, The First Hospital of Jilin University, Changchun, ChinaĪs a common and frequent clinical disease, peripheral nerve defect has caused a serious social burden, which is characterized by poor curative effect, long course of treatment and high cost.2Department of Orthopaedic Traumatology, The First Hospital of Jilin University, Changchun, China.1Department of Hand Surgery, The Second Hospital of Jilin University, Changchun, China.Shaochen Song 1, Xuejie Wang 1, Tiejun Wang 2, Qinghua Yu 3, Zheyu Hou 3, Zhe Zhu 1* and Rui Li 1*
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